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Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

Myeloperoxidase (MPO) and paraoxonase 1 (PON1) are high-density lipoprotein–associated (HDL-associated) proteins mechanistically linked to inflammation, oxidant stress, and atherosclerosis. MPO is a source of ROS during inflammation and can oxidize apolipoprotein A1 (APOA1) of HDL, impairing its ath...

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Detalhes bibliográficos
Main Authors: Huang, Ying, Wu, Zhiping, Riwanto, Meliana, Gao, Shengqiang, Levison, Bruce S., Gu, Xiaodong, Fu, Xiaoming, Wagner, Matthew A., Besler, Christian, Gerstenecker, Gary, Zhang, Renliang, Li, Xin-Min, DiDonato, Anthony J., Gogonea, Valentin, Tang, W.H. Wilson, Smith, Jonathan D., Plow, Edward F., Fox, Paul L., Shih, Diana M., Lusis, Aldons J., Fisher, Edward A., DiDonato, Joseph A., Landmesser, Ulf, Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754253/
https://ncbi.nlm.nih.gov/pubmed/23908111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67478
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