Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

Myeloperoxidase (MPO) and paraoxonase 1 (PON1) are high-density lipoprotein–associated (HDL-associated) proteins mechanistically linked to inflammation, oxidant stress, and atherosclerosis. MPO is a source of ROS during inflammation and can oxidize apolipoprotein A1 (APOA1) of HDL, impairing its ath...

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Hlavní autoři: Huang, Ying, Wu, Zhiping, Riwanto, Meliana, Gao, Shengqiang, Levison, Bruce S., Gu, Xiaodong, Fu, Xiaoming, Wagner, Matthew A., Besler, Christian, Gerstenecker, Gary, Zhang, Renliang, Li, Xin-Min, DiDonato, Anthony J., Gogonea, Valentin, Tang, W.H. Wilson, Smith, Jonathan D., Plow, Edward F., Fox, Paul L., Shih, Diana M., Lusis, Aldons J., Fisher, Edward A., DiDonato, Joseph A., Landmesser, Ulf, Hazen, Stanley L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754253/
https://ncbi.nlm.nih.gov/pubmed/23908111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67478
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