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T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies
Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2013
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/ https://ncbi.nlm.nih.gov/pubmed/23979161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938 |
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