T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...

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Main Authors: Hess, Constanze, Winkler, André, Lorenz, Alexandra K., Holecska, Vivien, Blanchard, Véronique, Eiglmeier, Susanne, Schoen, Anna-Lena, Bitterling, Josephine, Stoehr, Alexander D., Petzold, Dominique, Schommartz, Tim, Mertes, Maria M.M., Schoen, Carolin T., Tiburzy, Ben, Herrmann, Anne, Köhl, Jörg, Manz, Rudolf A., Madaio, Michael P., Berger, Markus, Wardemann, Hedda, Ehlers, Marc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/
https://ncbi.nlm.nih.gov/pubmed/23979161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938
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