Single Hemagglutinin Mutations That Alter both Antigenicity and Receptor Binding Avidity Influence Influenza Virus Antigenic Clustering

The hemagglutination inhibition (HAI) assay is the primary measurement used for identifying antigenically novel influenza virus strains. HAI assays measure the amount of reference sera required to prevent virus binding to red blood cells. Receptor binding avidities of viral strains are not usually t...

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Bibliografiske detaljer
Main Authors: Li, Yang, Bostick, David L., Sullivan, Colleen B., Myers, Jaclyn L., Griesemer, Sara B., StGeorge, Kirsten, Plotkin, Joshua B., Hensley, Scott E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754131/
https://ncbi.nlm.nih.gov/pubmed/23824816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01023-13
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