The Receptor Binding Domain of the New Middle East Respiratory Syndrome Coronavirus Maps to a 231-Residue Region in the Spike Protein That Efficiently Elicits Neutralizing Antibodies

The spike (S) protein of the recently emerged human Middle East respiratory syndrome coronavirus (MERS-CoV) mediates infection by binding to the cellular receptor dipeptidyl peptidase 4 (DPP4). Here we mapped the receptor binding domain in the S protein to a 231-amino-acid fragment (residues 358 to...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Mou, Huihui, Raj, V. Stalin, van Kuppeveld, Frank J. M., Rottier, Peter J. M., Haagmans, Bart L., Bosch, Berend Jan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754068/
https://ncbi.nlm.nih.gov/pubmed/23785207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01277-13
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares