Inhibition of Middle East Respiratory Syndrome Coronavirus Infection by Anti-CD26 Monoclonal Antibody

We identified the domains of CD26 involved in the binding of Middle East respiratory syndrome coronavirus (MERS-CoV) using distinct clones of anti-CD26 monoclonal antibodies (MAbs). One clone, named 2F9, almost completely inhibited viral entry. The humanized anti-CD26 MAb YS110 also significantly in...

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Detalhes bibliográficos
Main Authors: Ohnuma, Kei, Haagmans, Bart L., Hatano, Ryo, Raj, V. Stalin, Mou, Huihui, Iwata, Satoshi, Dang, Nam H., Bosch, Berend Jan, Morimoto, Chikao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838260/
https://ncbi.nlm.nih.gov/pubmed/24067970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02448-13
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