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Topological Analysis of HIV-1 Glycoproteins Expressed In Situ on Virus Surfaces Reveals Tighter Packing but Greater Conformational Flexibility than for Soluble gp120

In natural infection, antibodies interact with HIV-1 primarily through nonfunctional forms of envelope glycoproteins (Env), including uncleaved (UNC) gp160 and gp41 stumps. These antigens are important to fully characterize, as they may be decoys that promote nonneutralizing responses and may also b...

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書誌詳細
主要な著者: Tong, Tommy, Osawa, Keiko, Robinson, James E., Crooks, Ema T., Binley, James M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754051/
https://ncbi.nlm.nih.gov/pubmed/23740975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01145-13
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