Magnetic Fractionation and Proteomic Dissection of Cellular Organelles Occupied by the Late Replication Complexes of Semliki Forest Virus

Alphavirus replicase complexes are initially formed at the plasma membrane and are subsequently internalized by endocytosis. During the late stages of infection, viral replication organelles are represented by large cytopathic vacuoles, where replicase complexes bind to membranes of endolysosomal or...

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Bibliographic Details
Main Authors: Varjak, Margus, Saul, Sirle, Arike, Liisa, Lulla, Aleksei, Peil, Lauri, Merits, Andres
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754020/
https://ncbi.nlm.nih.gov/pubmed/23864636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01105-13
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