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Negative Regulation of RIG-I-Mediated Innate Antiviral Signaling by SEC14L1
Retinoic acid-inducible gene I (RIG-I) is a key sensor for recognizing nucleic acids derived from RNA viruses and triggers beta interferon (IFN-β) production. Because of its important role in antiviral innate immunity, the activity of RIG-I must be tightly controlled. Here, we used yeast two-hybrid...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3754010/ https://ncbi.nlm.nih.gov/pubmed/23843640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01073-13 |
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