Negative Regulation of RIG-I-Mediated Innate Antiviral Signaling by SEC14L1

Retinoic acid-inducible gene I (RIG-I) is a key sensor for recognizing nucleic acids derived from RNA viruses and triggers beta interferon (IFN-β) production. Because of its important role in antiviral innate immunity, the activity of RIG-I must be tightly controlled. Here, we used yeast two-hybrid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Meng-Tong, Di, Wei, Xu, Hao, Yang, Yong-Kang, Chen, Hai-Wei, Zhang, Fei-Xiong, Zhai, Zhong-He, Chen, Dan-Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754010/
https://ncbi.nlm.nih.gov/pubmed/23843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01073-13
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