Retinal Not Systemic Oxidative and Inflammatory Stress Correlated with VEGF Expression in Rodent Models of Insulin Resistance and Diabetes

PURPOSE. To correlate changes between VEGF expression with systemic and retinal oxidative stress and inflammation in rodent models of obesity induced insulin resistance and diabetes. METHODS. Retinal VEGF mRNA and protein levels were assessed by RT-PCR and VEGF ELISA, respectively. Urinary 8-hydroxy...

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Main Authors: Mima, Akira, Qi, Weier, Hiraoka-Yamomoto, Junko, Park, Kyoungmin, Matsumoto, Motonobu, Kitada, Munehiro, Li, Qian, Mizutani, Koji, Yu, Edward, Shimada, Takeshi, Lee, Jongsoon, Shoelson, Steven E., Jobin, Christian, Rask-Madsen, Christian, King, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753893/
https://ncbi.nlm.nih.gov/pubmed/23197686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10207
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