Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy

This study characterizes the effect of glucose-induced activation of protein kinase Cδ (PKCδ) and Src homology-2 domain-containing phosphatase-1 (SHP-1) expression on vascular endothelial growth factor (VEGF) actions in glomerular podocytes in cultures and in glomeruli of diabetic rodents. Elevation...

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Detalhes bibliográficos
Main Authors: Mima, Akira, Kitada, Munehiro, Geraldes, Pedro, Li, Qian, Matsumoto, Motonobu, Mizutani, Koji, Qi, Weier, Li, Chenzhong, Leitges, Michael, Rask-Madsen, Christian, King, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382088/
https://ncbi.nlm.nih.gov/pubmed/22499584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-202994
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