Genetic Adjuvantation of Recombinant MVA with CD40L Potentiates CD8 T Cell Mediated Immunity

Modified vaccinia Ankara (MVA) is a safe and promising viral vaccine vector that is currently investigated in several clinical and pre-clinical trials. In contrast to inactivated or sub-unit vaccines, MVA is able to induce strong humoral as well as cellular immune responses. In order to further impr...

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Bibliographic Details
Main Authors: Lauterbach, Henning, Pätzold, Juliane, Kassub, Ronny, Bathke, Barbara, Brinkmann, Kay, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753717/
https://ncbi.nlm.nih.gov/pubmed/23986761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00251
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