NLRC4 Inflammasome-Driven Immunogenicity of a Recombinant MVA Mucosal Vaccine Encoding Flagellin

Bacterial flagellin enhances innate and adaptive immune responses and is considered a promising adjuvant for the development of vaccines against infectious diseases and cancer. Antigen-presenting cells recognize flagellin with the extracellular TLR5 and the intracellular NLRC4 inflammasome-mediated...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Sanos, Stephanie L., Kassub, Ronny, Testori, Marco, Geiger, Marlene, Pätzold, Juliane, Giessel, Raphael, Knallinger, Johanna, Bathke, Barbara, Gräbnitz, Fabienne, Brinkmann, Kay, Chaplin, Paul, Suter, Mark, Hochrein, Hubertus, Lauterbach, Henning
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787573/
https://ncbi.nlm.nih.gov/pubmed/29416534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01988
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