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Multiplexed Microcolumn-Based Process for Efficient Selection of RNA Aptamers

[Image: see text] We describe a reusable microcolumn and process for the efficient discovery of nucleic acid aptamers for multiple target molecules. The design of our device requires only microliter volumes of affinity chromatography resin—a condition that maximizes the enrichment of target-binding...

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書誌詳細
主要な著者: Latulippe, David R., Szeto, Kylan, Ozer, Abdullah, Duarte, Fabiana M., Kelly, Christopher V., Pagano, John M., White, Brian S., Shalloway, David, Lis, John T., Craighead, Harold G.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2013
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753675/
https://ncbi.nlm.nih.gov/pubmed/23398198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400105e
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