High-throughput binding characterization of RNA aptamer selections using a microplate-based multiplex microcolumn device

We describe a versatile 96-well microplate-based device that utilizes affinity microcolumn chromatography to complement downstream plate-based processing in aptamer selections. This device is reconfigurable and is able to operate in serial and/or parallel mode with up to 96 microcolumns. We demonstr...

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Bibliografiske detaljer
Main Authors: Szeto, Kylan, Reinholt, Sarah J., Duarte, Fabiana M., Pagano, John M., Ozer, Abdullah, Yao, Li, Lis, John T., Craighead, Harold G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2014
Fag:
Note
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975076/
https://ncbi.nlm.nih.gov/pubmed/24553662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-7661-7
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