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Microfluidic single vessel production of hypoxia tracer 1H-1-(3-[(18)F]-fluoro-2-hydroxy-propyl)-2-nitro-imidazole ([(18)F]-FMISO)
We report an automated synthesis of [18F]-FMISO utilizing a prototype microfluidic radiochemistry module. The instrument allows for production of the tracer with 58% ± 2% (11 runs) decay corrected yield. Total time of production, including synthesis and purification averages 60 minutes. Use of the m...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753664/ https://ncbi.nlm.nih.gov/pubmed/22871433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2012.05.022 |
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