Automated radiosynthesis of two (18)F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [(18)F]FMISO and [(18)F]PM-PBB3, via [(18)F]epifluorohydrin

BACKGROUND: [(18)F]Fluoromisonidazole ([(18)F]FMISO) and 1-[(18)F]fluoro-3-((2-((1E,3E)-4-(6-(methylamino)pyridine-3-yl)buta-1,3-dien-1-yl)benzo[d]thiazol-6-yl)oxy)propan-2-ol ([(18)F]PM-PBB3 or [(18)F]APN-1607) are clinically used radiotracers for imaging hypoxia and tau pathology, respectively. Bo...

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Dades bibliogràfiques
Publicat a:EJNMMI Radiopharm Chem
Autors principals: Ohkubo, Takayuki, Kurihara, Yusuke, Ogawa, Masanao, Nengaki, Nobuki, Fujinaga, Masayuki, Mori, Wakana, Kumata, Katsushi, Hanyu, Masayuki, Furutsuka, Kenji, Hashimoto, Hiroki, Kawamura, Kazunori, Zhang, Ming-Rong
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8272768/
https://ncbi.nlm.nih.gov/pubmed/34245396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-021-00138-9
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