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Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation

The initiation of protein synthesis plays an essential regulatory role in human biology. At the center of the initiation pathway, the 13-subunit eukaryotic translation initiation factor 3 (eIF3) controls access of other initiation factors and mRNA to the ribosome by unknown mechanisms. Using electro...

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Detalhes bibliográficos
Main Authors: Sun, Chaomin, Querol-Audí, Jordi, Mortimer, Stefanie A., Arias-Palomo, Ernesto, Doudna, Jennifer A., Nogales, Eva, Cate, Jamie H. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753635/
https://ncbi.nlm.nih.gov/pubmed/23766293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt510
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