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Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunit
Translation of the hepatitis C virus genomic RNA initiates from an internal ribosome entry site (HCV IRES) in its 5′ untranslated region and requires a minimal subset of translation initiation factors to occur, namely eukaryotic initiation factors eIF2 and eIF3. Low-resolution structural information...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975054/ https://ncbi.nlm.nih.gov/pubmed/20816988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.054 |
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