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The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit

The hepatitis C virus (HCV) genomic RNA contains an internal ribosome entry site (IRES) in its 5′ untranslated region, the structure of which is essential for viral protein translation. The IRES includes a predicted pseudoknot interaction near the AUG start codon, but the results of previous studies...

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Detalhes bibliográficos
Main Authors: Berry, Katherine E., Waghray, Shruti, Doudna, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905755/
https://ncbi.nlm.nih.gov/pubmed/20584896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2197210
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