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Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning
Translation of Hepatitis C viral proteins requires an internal ribosome entry site (IRES) located in the 5′ untranslated region of the viral mRNA. The core domain of the Hepatitis C virus (HCV) IRES contains a four-way helical junction that is integrated within a predicted pseudoknot. This domain is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209822/ https://ncbi.nlm.nih.gov/pubmed/22000514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.08.002 |
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