Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)

Protein fate in higher eukaryotes is controlled by three complexes that share conserved architectural elements: the proteasome, COP9 signalosome, and eukaryotic translation initiation factor 3 (eIF3). Here we reconstitute the 13-subunit human eIF3 in Escherichia coli, revealing its structural core t...

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Detalhes bibliográficos
Main Authors: Sun, Chaomin, Todorovic, Aleksandar, Querol-Audí, Jordi, Bai, Yun, Villa, Nancy, Snyder, Monica, Ashchyan, John, Lewis, Christopher S., Hartland, Abbey, Gradia, Scott, Fraser, Christopher S., Doudna, Jennifer A., Nogales, Eva, Cate, Jamie H. D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251073/
https://ncbi.nlm.nih.gov/pubmed/22135459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116821108
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