Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity

Base excision repair (BER) and mismatch repair (MMR) pathways play an important role in modulating cis-Diamminedichloroplatinum (II) (cisplatin) cytotoxicity. In this article, we identified a novel mechanistic role of both BER and MMR pathways in mediating cellular responses to cisplatin treatment....

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Autors principals: Kothandapani, Anbarasi, Sawant, Akshada, Dangeti, Venkata Srinivas Mohan Nimai, Sobol, Robert W., Patrick, Steve M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753620/
https://ncbi.nlm.nih.gov/pubmed/23761438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt479
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