Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutation Selection during In Vitro Exposure to Tenofovir Alone or Combined with Abacavir or Lamivudine

Mutations selected or deselected during passage of human immunodeficiency virus strain HXB2 or resistant variants with tenofovir (TFV), abacavir (ABC), and lamivudine (3TC) differed depending on the drug combination and virus genotype. In the wild-type virus, TFV-ABC and TFV-3TC selected K65R (with...

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Hlavní autoři: Stone, Chris, Ait-Khaled, Mounir, Craig, Charles, Griffin, Philip, Tisdale, Margaret
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC375323/
https://ncbi.nlm.nih.gov/pubmed/15047556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1413-1415.2004
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