Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutation Selection during In Vitro Exposure to Tenofovir Alone or Combined with Abacavir or Lamivudine

Mutations selected or deselected during passage of human immunodeficiency virus strain HXB2 or resistant variants with tenofovir (TFV), abacavir (ABC), and lamivudine (3TC) differed depending on the drug combination and virus genotype. In the wild-type virus, TFV-ABC and TFV-3TC selected K65R (with...

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Detalhes bibliográficos
Main Authors: Stone, Chris, Ait-Khaled, Mounir, Craig, Charles, Griffin, Philip, Tisdale, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC375323/
https://ncbi.nlm.nih.gov/pubmed/15047556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1413-1415.2004
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