Relationship between Antiviral Activity and Host Toxicity: Comparison of the Incorporation Efficiencies of 2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine-Triphosphate Analogs by Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Human Mitochondrial DNA Polymerase

Antzeko izenburuak

• Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys.
  nork: Schinazi, R F, et al.
  Argitaratua: (1992)
• Safety, Pharmacokinetics, and Efficacy of (+/−)-β-2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine with Efavirenz and Stavudine in Antiretroviral-Naïve Human Immunodeficiency Virus-Infected Patients
  nork: Herzmann, C., et al.
  Argitaratua: (2005)
• Pharmacokinetics of (-)-2'-3'-dideoxy-3'-thiacytidine in woodchucks.
  nork: Rajagopalan, P, et al.
  Argitaratua: (1996)
• Pharmacodynamics of (−)-β-2′,3′-Dideoxy-3′-Thiacytidine in Chronically Virus-Infected Woodchucks Compared to Its Pharmacodynamics in Humans
  nork: Hurwitz, Selwyn J., et al.
  Argitaratua: (1998)
• A New Point Mutation (P157S) in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Confers Low-Level Resistance to (−)-β-2′,3′-Dideoxy-3′-Thiacytidine
  nork: Smith, Robert A., et al.
  Argitaratua: (1999)