The NLRP12 inflammasome recognizes Yersinia pestis

Yersinia pestis, the causative agent of plague, is able to suppress production of inflammatory cytokines IL-18 and IL-1β, which are generated through caspase-1–activating nucleotide-binding domain and leucine-rich repeat (NLR)-containing inflammasomes. Here, we sought to elucidate the role of NLRs a...

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Detalhes bibliográficos
Main Authors: Vladimer, Gregory I., Weng, Dan, Paquette, Sara W. Montminy, Vanaja, Sivapriya Kailasan, Rathinam, Vijay A. K., Aune, Marie Hjelmseth, Conlon, Joseph E., Burbage, Joseph J., Proulx, Megan K., Liu, Qin, Reed, George, Mecsas, Joan C., Iwakura, Yoichiro, Bertin, John, Goguen, Jon D., Fitzgerald, Katherine A., Lien, Egil
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753114/
https://ncbi.nlm.nih.gov/pubmed/22840842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.07.006
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