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Evaluation of the Role of LcrV-Toll-Like Receptor 2-Mediated Immunomodulation in the Virulence of Yersinia pestis

Pathogenic members of the Yersinia genus require the translocator protein LcrV for proper function of the type III secretion apparatus, which is crucial for virulence. LcrV has also been reported to play an independent immunosuppressive role via the induction of interleukin-10 (IL-10) through stimul...

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Hlavní autoři: Pouliot, Kimberly, Pan, Ning, Wang, Shixia, Lu, Shan, Lien, Egil, Goguen, Jon D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932965/
https://ncbi.nlm.nih.gov/pubmed/17438030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01644-06
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