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Involvement of CD8+ T Cell-mediated Immune Responses in LcrV DNA Vaccine Induced Protection against Lethal Y. Pestis Challenge

Yersinia pestis (Y. pestis) is the causative pathogen of plague, a highly fatal disease for which an effective vaccine, especially against mucosal transmission, is still not available. Like many bacterial infections, antigen-specific antibody responses have been traditionally considered critical, if...

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Bibliographic Details
Main Authors: Wang, Shixia, Goguen, Jon D., Li, Fusheng, Lu, Shan
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079781/
https://ncbi.nlm.nih.gov/pubmed/21199697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.062
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