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Aβ42 neurotoxicity in primary co-cultures: Effect of apoE isoform and Aβ conformation
Autosomal dominant mutations that increase amyloid-β(1–42) (Aβ42) cause familial Alzheimer’s disease (AD), and the most common genetic risk factor for AD is the presence of the ε4 allele of apolipoprotein E (apoE). Previously, we characterized stable preparations of Aβ42 oligomers and fibrils and re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752940/ https://ncbi.nlm.nih.gov/pubmed/16837105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.05.024 |
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