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Klotho as a potential biomarker and therapy for acute kidney injury
Klotho is a single-pass transmembrane protein that is highly expressed in the kidney and is known to act as a coreceptor for fibroblast growth factor 23. The extracellular domain can be produced independently or shed from membrane-bound Klotho and functions as an endocrine substance with multiple fu...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752896/ https://ncbi.nlm.nih.gov/pubmed/22664739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2012.92 |
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