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Klotho as a potential biomarker and therapy for acute kidney injury

Klotho is a single-pass transmembrane protein that is highly expressed in the kidney and is known to act as a coreceptor for fibroblast growth factor 23. The extracellular domain can be produced independently or shed from membrane-bound Klotho and functions as an endocrine substance with multiple fu...

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Detalhes bibliográficos
Main Authors: Hu, Ming-Chang, Moe, Orson W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752896/
https://ncbi.nlm.nih.gov/pubmed/22664739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2012.92
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