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Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice

PURPOSE: Molecular targeting of cellular signaling pathways is a promising approach in cancer therapy, but often fails to achieve sustained benefit because of the activation of collateral cancer cell survival and proliferation pathways. We tested the hypothesis that a combination of targeted agents...

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Autors principals: Pawaskar, Dipti K., Straubinger, Robert M., Fetterly, Gerald J., Hylander, Bonnie H., Repasky, Elizabeth A., Ma, Wen W., Jusko, William J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752659/
https://ncbi.nlm.nih.gov/pubmed/23455452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-013-2117-x
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