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Interactions of Everolimus and Sorafenib in Whole Blood Lymphocyte Proliferation

PURPOSE: Everolimus is an immunosuppressant that blocks growth factor-mediated proliferation of hematopoietic cells by targeting the mammalian target of rapamycin (mTOR). Sorafenib is a multikinase inhibitor that inhibits cell proliferation by arresting cells in the G0–G1 phase of the cell cycle. Th...

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Hlavní autoři: Pawaskar, Dipti K., Straubinger, Robert M., Fetterly, Gerald J., Ma, Wen W., Jusko, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726064/
https://ncbi.nlm.nih.gov/pubmed/23151723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0909-z
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