The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice

BACKGROUND: Apo2L/TRAIL has considerable promise for cancer therapy based on the fact that this member of the tumor necrosis factor family induces apoptosis in the majority of malignant cells, while normal cells are more resistant. Furthermore, in many cells, when Apo2L/TRAIL is combined with chemot...

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Autores principales: Hylander, Bonnie L, Pitoniak, Rose, Penetrante, Remedios B, Gibbs, John F, Oktay, Dilek, Cheng, Jinrong, Repasky, Elizabeth A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156958/
https://ncbi.nlm.nih.gov/pubmed/15943879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-3-22
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