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Experimental and natural infections in MyD88‐ and IRAK‐4‐deficient mice and humans

Most Toll‐like‐receptors (TLRs) and interleukin‐1 receptors (IL‐1Rs) signal via myeloid differentiation primary response 88 (MyD88) and interleukin‐1 receptor‐associated kinase 4 (IRAK‐4). The combined roles of these two receptor families in the course of experimental infections have been assessed i...

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Autori principali: von Bernuth, Horst, Picard, Capucine, Puel, Anne, Casanova, Jean‐Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752658/
https://ncbi.nlm.nih.gov/pubmed/23255009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242683
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