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Infectious Diseases in Patients with IRAK-4, MyD88, NEMO, or IκBα Deficiency

Summary: Autosomal recessive IRAK-4 and MyD88 deficiencies predispose affected patients to recurrent invasive pyogenic bacterial infection. Both defects result in the selective impairment of cellular responses to Toll-like receptors (TLRs) other than TLR3 and of cellular responses to most interleuki...

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Detalhes bibliográficos
Main Authors: Picard, Capucine, Casanova, Jean-Laurent, Puel, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131061/
https://ncbi.nlm.nih.gov/pubmed/21734245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.00001-11
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