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β-Turn Sequences Promote Stability of Peptide Substrates for Kinases within the Cytosolic Environment

A strategy was developed to extend the lifetime of an peptide-based substrate for Abl kinase in the cytosolic environment. Small β-turn structures were added to the peptide’s N-terminus to block entry into peptidase catalytic sites. The influence of the size of the β-turn and two covalent cross-link...

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Bibliografische gegevens
Hoofdauteurs: Yang, Shan, Proctor, Angela, Cline, Lauren L., Houston, Kaiulani M., Waters, Marcey L., Allbritton, Nancy L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752283/
https://ncbi.nlm.nih.gov/pubmed/23785707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3an00874f
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