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Effect of the DEF motif on phosphorylation of peptide substrates by ERK

MAP kinase ERK maintains specificity by binding to docking sites such as the DEF domain or D domain. It was previously shown that appending peptides derived from D domains to a substrate peptide increased apparent efficiency of peptide phosphorylation while preserving its apparent specificity for ER...

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Detalhes bibliográficos
Main Authors: Fernandes, Neychelle, Allbritton, Nancy .L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745210/
https://ncbi.nlm.nih.gov/pubmed/19615338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.07.049
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