Hippo pathway effector Yap promotes cardiac regeneration

The adult mammalian heart has limited potential for regeneration. Thus, after injury, cardiomyocytes are permanently lost, and contractility is diminished. In contrast, the neonatal heart can regenerate owing to sustained cardiomyocyte proliferation. Identification of critical regulators of cardiomy...

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Detalles Bibliográficos
Main Authors: Xin, Mei, Kim, Yuri, Sutherland, Lillian B., Murakami, Masao, Qi, Xiaoxia, McAnally, John, Porrello, Enzo R., Mahmoud, Ahmed I., Tan, Wei, Shelton, John M., Richardson, James A., Sadek, Hesham A., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752208/
https://ncbi.nlm.nih.gov/pubmed/23918388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313192110
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