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Hippo pathway effector Yap promotes cardiac regeneration

The adult mammalian heart has limited potential for regeneration. Thus, after injury, cardiomyocytes are permanently lost, and contractility is diminished. In contrast, the neonatal heart can regenerate owing to sustained cardiomyocyte proliferation. Identification of critical regulators of cardiomy...

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Bibliografiske detaljer
Main Authors: Xin, Mei, Kim, Yuri, Sutherland, Lillian B., Murakami, Masao, Qi, Xiaoxia, McAnally, John, Porrello, Enzo R., Mahmoud, Ahmed I., Tan, Wei, Shelton, John M., Richardson, James A., Sadek, Hesham A., Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752208/
https://ncbi.nlm.nih.gov/pubmed/23918388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313192110
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