Programmatically Selected Multidrug-Resistant Strains Drive the Emergence of Extensively Drug-Resistant Tuberculosis in South Africa

BACKGROUND: South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included ofloxacin, kanamycin, ethionamide...

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主要な著者: Müller, Borna, Chihota, Violet N., Pillay, Manormoney, Klopper, Marisa, Streicher, Elizabeth M., Coetzee, Gerrit, Trollip, Andre, Hayes, Cindy, Bosman, Marlein E., Gey van Pittius, Nicolaas C., Victor, Thomas C., Gagneux, Sebastien, van Helden, Paul D., Warren, Robin M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751934/
https://ncbi.nlm.nih.gov/pubmed/24058399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070919
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