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Epistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis
Background and objectives: Multidrug resistant (MDR) bacteria are a growing threat to global health. Studies focusing on single antibiotics have shown that drug resistance is often associated with a fitness cost in the absence of drug. However, little is known about the fitness cost associated with...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868377/ https://ncbi.nlm.nih.gov/pubmed/24481187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eot003 |
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