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Strain diversity, epistasis and the evolution of drug resistance in Mycobacterium tuberculosis

Mycobacterium tuberculosis harbours little DNA sequence diversity compared to other bacteria. However, there is mounting evidence that strain-to-strain variation in this organism has been underestimated. Here we review our current understanding of the genetic diversity among M. tuberculosis clinical...

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Bibliographic Details
Main Authors: Borrell, Sònia, Gagneux, Sebastien
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122159/
https://ncbi.nlm.nih.gov/pubmed/21682802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-0691.2011.03556.x
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