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Transition bias influences the evolution of antibiotic resistance in Mycobacterium tuberculosis

Transition bias, an overabundance of transitions relative to transversions, has been widely reported among studies of the rates and spectra of spontaneous mutations. However, demonstrating the role of transition bias in adaptive evolution remains challenging. In particular, it is unclear whether suc...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Payne, Joshua L., Menardo, Fabrizio, Trauner, Andrej, Borrell, Sonia, Gygli, Sebastian M., Loiseau, Chloe, Gagneux, Sebastien, Hall, Alex R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532934/
https://ncbi.nlm.nih.gov/pubmed/31083647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000265
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