Programmatically Selected Multidrug-Resistant Strains Drive the Emergence of Extensively Drug-Resistant Tuberculosis in South Africa

BACKGROUND: South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included ofloxacin, kanamycin, ethionamide...

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Detalhes bibliográficos
Main Authors: Müller, Borna, Chihota, Violet N., Pillay, Manormoney, Klopper, Marisa, Streicher, Elizabeth M., Coetzee, Gerrit, Trollip, Andre, Hayes, Cindy, Bosman, Marlein E., Gey van Pittius, Nicolaas C., Victor, Thomas C., Gagneux, Sebastien, van Helden, Paul D., Warren, Robin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751934/
https://ncbi.nlm.nih.gov/pubmed/24058399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070919
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