Programmatically Selected Multidrug-Resistant Strains Drive the Emergence of Extensively Drug-Resistant Tuberculosis in South Africa

BACKGROUND: South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included ofloxacin, kanamycin, ethionamide...

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Bibliografiska uppgifter
Huvudupphovsmän: Müller, Borna, Chihota, Violet N., Pillay, Manormoney, Klopper, Marisa, Streicher, Elizabeth M., Coetzee, Gerrit, Trollip, Andre, Hayes, Cindy, Bosman, Marlein E., Gey van Pittius, Nicolaas C., Victor, Thomas C., Gagneux, Sebastien, van Helden, Paul D., Warren, Robin M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751934/
https://ncbi.nlm.nih.gov/pubmed/24058399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070919
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