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A Liposomal Drug Platform Overrides Peptide Ligand Targeting to a Cancer Biomarker, Irrespective of Ligand Affinity or Density

One method for improving cancer treatment is the use of nanoparticle drugs functionalized with targeting ligands that recognize receptors expressed selectively by tumor cells. In theory such targeting ligands should specifically deliver the nanoparticle drug to the tumor, increasing drug concentrati...

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Autori principali: Gray, Bethany Powell, McGuire, Michael J., Brown, Kathlynn C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751880/
https://ncbi.nlm.nih.gov/pubmed/24009717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072938
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